Running in the opposite direction to Zion Road is Kim Seng Road. Two one-way streets link Zion Road and Kim Seng Road. Kim Seng Walk sends traffic from Zion Road to Kim Seng Road while Kim Seng Promenade sends in the opposite direction. On the west side, Zion Road also branches to Kellock Road and Zion Close.
Zion Road was named after the residence of Reverend B.P. Keasberry, a 19th century Presbyterian missionary who ran a boarding school in Singapore. One of the students of this boarding school was Abu Bakar bin Temenggong Ibrahim, who later became the Sultan of Johor.