Khlong Phadung Krung Kasem (Thai: คลองผดุงกรุงเกษม ) is the third of the three concentric canals that ring the inner city of Bangkok, Thailand. Measuring a length of 5.5 km, it was bug in 1851, during the reign of King Rama IV, at a time when Bangkok was expanding outwards.
As with the two earlier canals, Khlong Phadung Krung Kasem to form a concentric ring. From the north to south, it starts near the Rama VIII Bridge, and flows in a southeasternly direction, with Luk Luang Road on its north bank and Krung Kasem Road on its south.
South of Lan Luang Road, the canal starts to bend heading south. It passes the Hualamphong Railway Station to its east, and continues south, with Mahaphurutharam Road to its east side. It passes by Wat Maha Phruttharam a short distance before emptying into the Chao Phraya River.